SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability
Abstract Innervation of the hypothalamic median eminence by Gonadotropin-Releasing Hormone (GnRH) neurons is vital to ensure puberty onset and successful reproduction.However, the molecular and cellular mechanisms underlying median eminence Sex Doll development and pubertal timing are incompletely understood.Here we show that Semaphorin-6A is stron